OXANDROLONE

In an attempt to compensate for the exogenous increase in androgens, the body may reduce testosterone production via testicular atrophy and inhibition of gonadotropic activity. Like other androgens, oxandrolone can cause or worsen acne and priapism (unwanted or prolonged erections). Women who are administered oxandrolone may experience virilization, irreversible development of masculine features such as voice deepening, hirsutism, menstruation abnormalities, male-pattern hair loss, and clitoral enlargement.
This structural element is what gives oxandrolone its distinctive chemical identity within the class of anabolic steroids. The overall structure of oxandrolone is distinguished by these modifications to the standard steroid nucleus, which contribute to its unique properties as an anabolic steroid. The reduced ratio of anabolic to androgenic activity of oxandrolone motivated its medical use in children and women because less androgenic effect implies less risk of virilization. As  cbtrends , the researchers stated, "although oxandrolone cannot be implicated as stimulatory in gynecomastia", a possible relationship should be considered in clinicians using oxandrolone in adolescents for growth stimulation. Because it is more anabolic than androgenic, women and those seeking less intense steroid regimens used it particularly often.
In the United States, the FDA's Endocrinologic and Metabolic Drugs Advisory Committee unanimously concluded in 1984 that there was no evidence of efficacy for oxandrolone.  Come comprare Anavar in modo sicuro  is a controlled substance in many countries, so non-medical use for purposes such as improving physique and performance has been generally illicit.
Like other AASs, oxandrolone is an agonist of the androgen receptor, similar to androgens such as testosterone and DHT. The gynecomastia developed during oxandrolone therapy in 19 of the boys and after the therapy was completed in 14 of the boys, and 10 of the boys had transient gynecomastia, while 23 had persistent gynecomastia that necessitated mastectomy. Unlike some AASs, oxandrolone does not generally cause gynecomastia because it is not aromatized into estrogenic metabolites. Because of these side effects, doses given to women and children are minimized and people are usually monitored for virilization and growth abnormalities.